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Metabolic Syndrome and Colorectal Cancer

What is Metabolic Syndrome?

Metabolic syndrome is a condition that is characterised by high blood pressure, increased levels of cholesterol and triglycerides, and low levels of HDL (“good” cholesterol). In addition, metabolic syndrome is associated with an increased risk of cardiovascular disease and colorectal cancer. But there are steps you can take to lower your risk of developing this disease. (1)

Increased circulating levels of inflammatory markers

Increased circulating levels of inflammatory markers are associated with metabolic syndrome. This may be important in explaining the progression of cardiovascular diseases. Several approaches may be used to reduce inflammation. These include diet, exercise, and use of anti-inflammatory agents. However, the relationship between inflammatory biomarkers and CVD has not been fully elucidated.

Using generalised linear models, we examined the relationship between inflammatory biomarkers and a measure of the trajectories of participants’ health over time. The trajectories were estimated in a mixed model incorporating interaction terms between age and protein levels. For participants in the 30-to-60-year-old age group, the 10th, 50th, and 90th percentiles of the mean inflammatory protein level were estimated. (2)


Our findings suggest that inflammatory markers have a higher association with cardiovascular comorbidities than lipid profiles. More studies are needed to assess the relationship between inflammatory biomarkers and cerebrovascular disease.

We studied the association between inflammatory biomarkers and CVD in a community-based multiethnic cohort of elderly participants. Participants were assessed at baseline and at follow-up 4.5 years later. The following inflammatory biomarkers were measured: C-reactive protein (CRP), IL-6, ACT, and GDF15.

Increased risk of cardiovascular disease

The term metabolic syndrome refers to a group of heart disease risk factors. It includes abdominal obesity, high triglycerides, and abnormal cholesterol levels. Metabolic syndrome also increases the risk of diabetes and stroke. However, the risk of these diseases does not necessarily increase when the individual components of MetS are present.

To evaluate the relationship between MetS and cardiovascular risk, Cox proportional hazards models were used. All-cause mortality and CVD were included in the model. For example, the CVD risk was calculated for hypothetical female and male cases aged 45 and 65 years.

In addition to all-cause mortality, MetS components were independently associated with myocardial infarction, stroke, and mortality from CVD. A multistate MetS-related Markov process was used to analyse dynamic changes between MetS and MetS.

Age is a negative factor in the regression from MetS to FMD. This provides insight into early health promotion for the young age group.

Cardiovascular risk is a recurrent theme of the study. Diet, exercise, and behavioural counselling can lower these risks more effectively than dietary changes alone.

Increased risk of colorectal cancer

In the present study we aimed to examine the relationship between colorectal cancer and metabolic syndromes. A multicenter case-control study was conducted on 140 histologically confirmed cases of CRC. The results indicated that a combination of high waist circumference and elevated fasting blood glucose was associated with a 126% increased risk of CRC.

Despite the fact that this is a relatively small study, the magnitude of the risk was on par with the risk attributed to a family history of colonic adenomas. However, further prospective investigation is needed to establish a more definitive connection between MetS and CRC.

The aforementioned is only the simplest of the three definitions used. A Cox proportional hazards regression model was used to estimate the association between each MetS component and CRC risk.

Adiponectin is known to have anti-inflammatory properties. This compound is also believed to have insulin-sensitising effects. Obesity also promotes inflammatory signals, which may play a role in cancer development.

Lifestyle changes can reduce your risk

If you want to reduce your risk of metabolic syndrome, you need to make certain lifestyle changes. This includes changing your diet and exercising regularly. These behaviours can reduce your cholesterol, blood pressure, and blood sugar levels.

It may also help to follow your doctor’s instructions. Some people will need medicines to control their blood pressure, cholesterol, and other metabolic syndrome risks. You should consult your doctor before starting any new behaviour or program.

If you have any signs of high blood pressure, high cholesterol, or high triglyceride levels, you should see your healthcare provider. They can run tests to determine your metabolic syndrome. Once your health condition is under control, you can reduce your chances of heart attack and stroke.

For most patients with metabolic syndrome, dietary changes can help reduce insulin resistance, which causes high blood sugar. A healthy diet should include lots of fruits and vegetables, whole grains, and lean proteins. Limiting saturated fats and processed foods is important. (5)

About Us

CannaTelehealth, specialises in providing online consultations for various healthcare needs, including assistance with alcohol addiction. Our platform is designed to facilitate the use of advanced telehealth technology by medical professionals, ensuring the security and privacy of patient information in compliance with regulations.

We have developed an online system that simplifies the process of booking appointments with qualified and experienced General Practitioners, Nurse Practitioners, who can assist patients in accessing prescriptions for Medicinal Cannabis for their medical conditions. Our telehealth system is fully supported by our clinical team, guaranteeing that all consultations are conducted by appropriately qualified healthcare professionals.

Our doctors are authorised to prescribe Medicinal Cannabis under Schedule 8 of the Therapeutic Goods Act. In the initial consultation, your nurse or doctor will collaborate with you to determine the suitability of Medicinal Cannabis for your specific symptoms and conditions. If deemed appropriate, they will then apply for TGA approval for your electronic prescription, which can be presented at your pharmacy of choice.

Medical Cannabis Doctors Online Treatment and Consults

CannaTelehealth’s doctors have extensive experience in assessing patients for medicinal cannabis. Prior to having an online consultation with our healthcare professionals it is a good idea to write down your questions before your consultation so that you don’t forget them.

Our doctors will review your medical history and confirm that you meet the criteria for a medicinal cannabis prescription under the Therapeutic Goods Administration (TGA) Special Access Scheme. We will then either prescribe medication through the Authorised Prescriber pathway or submit your application to the TGA and you should receive your product within 2 business days.

All our doctors are trained under the TGA authorised prescriber scheme and have detailed knowledge of how cannabis affects the body. Our doctors are also able to recommend the best dosage and type of cannabis for your condition. Our doctors are able to prescribe all forms of medicinal cannabis including capsules, tinctures, sprays and vape cartridges.

The cost of your medical cannabis will vary depending on your condition and the specific product that is recommended for you.

Our clinic offers bulk billing for patients who have been approved by the DVA. This is worth checking for your eligibility criteria for this discounted online consultation.

Book a consultation – Follow the simple steps to engaging with an online health professional who will assess your eligibility for alternative treatments such as medicinal cannabis and what might be the cause of your chronic pain.

To contact us at CannaTelehealth you can either go directly to the website and add your details directly to our ‘Contact Us Form’ We will contact you within 1 hour. Normally our online healthcare professionals who are pain medicine specialists will have a booking time within 1 day if suitable. Alternatively you may contact us via info@cannatelehealth.com.au.


  1. https://www.healthdirect.gov.au/metabolic-syndrome
  2. Searching for Factors Raising the Incidence of Metabolic Syndrome Among 45-60-Year-Old WomenSzkup Małgorzata 1, Brodowski Jacek 2, Owczarek Aleksander Jerzy 3, Choręza Piotr 3, Jurczak Anna 4, Grochans Elżbieta 1Aging Dis. 2018 Oct 1;9(5):831-842. doi: 10.14336/AD.2017.1027. eCollection 2018 Oct.
  3. Dynamics of detailed components of metabolic syndrome associated with the risk of cardiovascular disease and death Ting-Yu Lin 1, Kuo-Liong Chien 1 2, Yueh-Hsia Chiu 3 4, Pi-Chun Chuang 5 6, Ming-Fang Yen 7, Hsiu-Hsi Chen 8Sci Rep. 2021 Feb 11;11(1):3677. doi: 10.1038/s41598-021-83118-y.
  4. Association between Metabolic Syndrome and CancerMehmet Uzunlulu 1, Ozge Telci Caklili, Aytekin Oguz Ann Nutr Metab. 2016;68(3):173-9. doi: 10.1159/000443743. Epub 2016 Feb 20.
  5. The Global Epidemic of the Metabolic SyndromeMohammad G Saklayen 1 Curr Hypertens Rep. 2018 Feb 26;20(2):12. doi: 10.1007/s11906-018-0812-z.

Our Healthcare professionals provide consultations on a long list of conditions.